A panel of judges unanimously ruled that the interventions were not in accordance with science and proven experience, according to a statement released today. What Is Benita Alexander Doing Now? She Was Conned Colorado The university board was dismissed and even Harriet Wallberg, whod moved on to become the chancellor for all Swedish universities, lost her job. Colleagues accused him of manipulating his results, even warning of the harm caused by these so-called regenerative windpipes. The maximum prison sentence for causing bodily harm is 4 years. Meanwhile, Macchiarinis career soared. (LogOut/ The Karolinska Institute declined to comment for this article, noting only that Dr. Macchiarinis sentence may be appealed. In early 2014, four Karolinska doctors defied the reigning culture of silence by complaining about Macchiarini. That's when, Benita said, it hit her: She had given up a good job and spent $50,000 on a "bogus fantasy wedding" to a man who already had at least two families. Illinois The nine-centimeter transplant replaced all but two centimeters of her trachea. Her colleague had sent an article that said the pope would not be in Rome, or even Italy, on the day of their wedding. The donor was a young man (identifying details are being withheld to protect privacy). And Murphy found that Macchiarinis claims about the wedding were almost all untrue and that the surgeon was married and had been for nearly 30 years. As it was built from Claudias own cells, she didnt need to be on any risky immunosuppressant drugs. So I called and called till I got an appointment., Dr. Genden said Ms. Sein beseeched him for the transplant, saying, You need to do this for me or Im going to end my life.. They reopened the case in 2020, this time charging Macchiarini on lesser counts of aggravated assault and severe bodily harm. Abu Dhabi About 11 centimeters (4 inches) long, one side curves like a halfpipe, composed of cartilage rings and ligaments. Surely, he got away with so much because he was considered an exception to the rules with more than a whiff of the Nobel about him. Prosecutors dropped the case a few months later, however, saying they didnt have sufficient evidence to prove manslaughter. Macchiarini had often boasted to Alexander of his famous friends. But, he added, Its an indirect technique. It takes time and can replace only the tracheas halfpipe side, so its not a complete tube.. Therefore, of all the medically ill individuals Paolo has ever provided a biological or synthetic implant to, at least 8 of them allegedly died due to his misconduct in research, failure to provide proper post-operative care, and/or his disregard for ethical practices. So far he has not been prosecuted in any of those countries. In their view, Macchiarini was certainly engaged in clinical research. I wasnt lying exactly, just Ive never in my experience witnessed a fraud like this, with this level of international flair, Murphy told Vanity Fair. I could feel it in my lungs.. A High-Flying Italian Surgeons Fall From Grace, https://www.nytimes.com/2022/06/17/world/europe/macchiarini-windpipe-surgeon-deaths.html. It did much the same for Macchiarinis windpipe replacements. An independent investigator agreed. 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That was a very smart idea to help maintain the fragile blood supply of the airway by leaving the esophagus in place behind it, Dr. Patterson said. Emanuela Pecchia [Paolo Macchiarini Wife] Biography, Seven of the eight patients Paolo inserted tracheas into have died. He was born in Basel, Switzerland to Italian parents. Likewise the secretary-general of the Nobel Committee. Ohio Dr. Genden also transplanted the cricoid, cartilage cuffing the trachea, supplanting Ms. Seins completely destroyed cricoid. At night, when she connected her tracheal tube to a ventilator, the alarm kept going off to let people know that I stopped breathing, said Ms. Sein, who hated causing her family concern. Thats what Macchiarini told his fiancee. We now know that wasnt true. 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But for now, lets focus solely on his medical patients, shall we? Paolo Macchiarinis most notable patient is Claudia Castillo. Born in 1977, this Colombian living in Spain woman suffered from tuberculosis-damaged airways. Macchiarini shot to prominence back in 2008, when he created a new airway for Claudia Castillo, a young woman from Barcelona. But it did not work, and a court in Sweden has found him criminally liable for the harm Still, noting that previous attempts didnt show documented success, he cautioned that longer-term results were needed before the technique should be embraced, adding, Lets see how it works and how you can do it in more patients.. Paolo was a world-renowned surgeon who spoke six languages, mingled with the global elite, and resembled George Clooney. But of 20 patients, including children, most ultimately died, and scientists said Dr. Macchiarini misrepresented data and exaggerated his techniques effectiveness. At any rate, some of his most powerful friends were themselves Nobel judges until, with his fall from grace, they fell too. The charismatic Italian surgeon who designed it foresaw a future where hearts and lungs could be made from plastic, and organ donations became a thing of the past. I have to expose him.". The surgeons defense attorney, Bjrn Hurtig, said his client was considering an appeal. As per Dont yet have access? Even the jewelry he had given her was Few people at Karolinska, especially among those in power, knew enough about it to appreciate Delaeres claims. After several weeks in recovery, she is home. The media began calling him "Dr. Frankenstein" and said that he committed "the world's biggest medical fraud.". And fooled almost everyone. This thing came to life, Dr. Genden marveled, and we were like, Holy smokes, weve done it.. They didnt. Around the same time, an article in Vanity Fair described how Macchiarini had misled a girlfriendan NBC news producer working on a flattering documentary about his surgeriesinto thinking they would be married in a ceremony attended by the Clintons and Obamas and officiated by the pope. Almost immediately after she was fitted with a synthetic trachea in August 2012, Ms. Cetirs condition began to rapidly deteriorate, according to the courts written judgment. How we can build a clean and renewable future. The Italian surgeon and his Italian wife Emanuela Pecchia have one son and one daughter. Its fascinating to rewatch as a lesson on how not to report on medical science. Your tax-deductible contribution plays a critical role in sustaining this effort. Thailand Paolo Macchiarini Georgia A review of public records in Italy found that Paolo was never divorced from Emanuela Pecchia, his wife of nearly 30 years. Every year, it gives science a show-business makeover, picking out from the mass of medical researchers those individuals deserving of superstardom. What comes next after Texas school shooting? Thereafter it was all over the news. That drama began about a decade ago when Dr. Paolo Macchiarini, working at Swedens famed Karolinska Institute, garnered headlines and accolades for replacing Kevin Belingon On May 13, Alexander left her job. The idea is that scientific progress is driven by the genius of a few. She would later discover that the woman in Barcelona had been living with Paolo for years, but that there were several other women in his life as well. The first person to receive one of these was Andemariam Beyene, an Eritrean doctoral student in geology at the University of Iceland. Benita decided to get in touch with private investigator Frank Murphy. Reports of their success always seemed like hot air to him. Paolo Macchiarini is exposed Reality struck Alexander's fantasy romance eight weeks before she was supposed to marry Macchiarini in 2015, when she received an email from a colleague with the subject line saying, "The Pope." As for Keziah Shorten, who suffered from trachea cancer, Paolo Macchiarini did a transplant on her on July 13, 2010, which failed the very next year. Any woman would swoon for such a catch! They exchange their vows in Italy. Japan There are people who go to jail for 5 years for not paying their taxes. The tube was necessary because her trachea the airway leading to the lungs had become damaged after she spent weeks on a ventilator for a severe asthma attack in 2014. Its like when you get on a rocket ship., At times, he felt in a dreamlike state, he said. His findings at the time concluded that Dr. Macchiarini had committed scientific misconduct, but this was ultimately ignored by the universitys leadership who chose to clear the Italian surgeon. She became close to Paolo as she opened her heart to him about how hard it was for her daughter, then nine years old, to lose her father. They recently published an article in the New England Journal of Medicine admitting that stem cell research has mostly failed to live up to its therapeutic promise. They allowed Macchiarini to continue his work as a visiting professor with a research lab. Photographs document Ms. Seins trachea transformation: Her old windpipe looks raw and red, her new one smooth as porcelain. This was Macchiarinis first big success. Surgeon Paolo Macchiarini was hailed for turning the dream of regenerative medicine into a reality until he was exposed as a con artist and false prophet. Thats what our experience of medical research leads us to suspect. Plus: NYC sixth-grader struck and killed by stray bullet; New Hampshire police search for person of interest in double homicide; Fyre Festival fraudster released early from prison; and manhunt continues for escaped Texas prisoner. A review of public records in Italy found that Paolo was never divorced from Emanuela Pecchia, his wife of nearly 30 years. From that moment on, she made a proposal to Paolo Macchiarini, and Dateline planned to publish the story. Washington Swedish television broadcast a three-part expos of Paolo's work called Experimenten, which argued that the artificial windpipes did more harm than good and were actually rotting away inside his patients' bodies. As of the time of that judgment, Macchiarini had not been prosecuted in other countries where he implanted his artificial windpipes, and it was unclear whether he was still practicing medicine, the Times adds. She says it may mean the judges thought he and the patients believed time was short and options were few. But according to reports, Paolo cheated on his Emanuela Pecchia. I cant do this anymore, Sonia Sein told herself, her family and her doctor. The grant ended in spring 2017. Stem cell research is a hot field of science and, according to statistics, also a rather scandal-prone one. An unhappy result of this is the rise of pseudo-scientific therapies. Massachusetts Macchiarini was turning the dream of regenerative medicine into a reality. Not only that, they later covered it up.. February 28, 2022 Emanuela Pecchia is famously known as the wife of popular Swiss-born Italian thoracic surgeon, Paolo Macchiarini. Back in New York, Benita found herself unable to stop thinking about Paolo's patients. Paolo grew close to Alexander's daughter [Investigation Discovery], He was incredibly charming, worldly smart, sophisticated, and seemed very gentle," Benita told CrimeFeed. We will send you a maximum of two emails in, We will be in touch to remind you to contribute. KI fired Macchiarini in March 2016, 2 months after the Swedish documentary came out. If she talked for over five minutes, she had to stop because I couldnt breathe.. He was eventually dismissed from Karolinska. And after hiring a private investigator, Ms Alexander found that Dr Macchiarini, pictured, was a man of more modest means living in Barcelona and that he was still married to his wife of 30 years Ms Alexander told Vanity Fair: 'I just didn't want to put two and two together. Stem cell brain implants could 'slow ageing and extend life', study shows, offering to treat just about any ailment you can name, Pregnant women's stem cells could treat osteoporosis, say scientists. Macchiarini is known for his research fraud and manipulative behavior. In September, a Swedish prosecutor indicted him on aggravated assault charges related to three trachea transplants. Nor did they impress the institutes ethics council when Delaere lodged a formal complaint. After being dismissed from the institute, he worked at the Kazan Federal University in Kazan, Russia. He did this by chemically stripping away the cells of a windpipe taken from a deceased donor; he then seeded the bare scaffold with stem cells taken from Castillos own bone marrow. Please make a tax-deductible gift today. A genius is a revolutionary by definition, a risk-taker and a law-breaker. Since this was radically new, Macchiarini and his colleagues should have tested it on animals first. According to the magazine, in 2012 he was charged in Italy with attempted aggravated fraud related to alleged efforts to persuade very ill patients to undergo radical surgery at facilities where he had privileges. She visits Mount Sinai weekly for blood work. This set a dangerous example. For the respect of privacy, his wifes identity is not revealed on the internet. He convinced the Karolinska Institute that this could make them famous, and they just let him do it. His operation was on June 9, 2011, at the Karolinska University Hospital, where he received the upgraded plastic trachea made at University College London. (The big exception is blood stem cell transplantation, which has been saving the lives of people with leukemia and other cancers of the blood for decades.). However, the serious complications that Castillo suffered were, for a long time, kept very quiet. The operation, performed at one of the worlds most prestigious medical universities, part of the Karolinska Institute in Stockholm, was hailed as revolutionary. The first season of both the Peacock series and the Wondery podcast of the same name told the story of Christopher Duntsch, a former neurosurgeon now serving a life sentence for botched surgeries that left more than 30 patients maimed or dead. Gretchen Vogel is a contributing correspondent for Science magazine based in Berlin, Germany.
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